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Showing posts with label Health. Show all posts
Showing posts with label Health. Show all posts

Thursday, 23 April 2020

April 23, 2020

Device that checks oxygen could be early warning system in coronavirus patients, doctor says


A New Hampshire emergency room doctor says simple technology could save lives in the fight against the coronavirus. Dr. Richard Levitan, who has three decades of experience, volunteered last month at Bellevue Hospital in New York City for 10 days and shared what he learned in a New York Times op-ed.
Levitan told "CBS This Morning" co-host Gayle King that people could potentially detect coronavirus earlier by checking their oxygen levels at home with pulse oximeters.
Read part of their conversation below.

Dr. Richard Levitan: People were sick for days, and then they only came in with shortness of breath, like, the day they presented. ... And they would arrive with oxygen levels that basically were incredible to us. I mean, almost unimaginable how people could be awake and alert and have oxygen levels that are half normal. … Normally we are 94% to 100% on these devices, these pulse oximeters that measure how much oxygen we have in our blood. And people were showing up with oxygen levels of 50%. Now, this matches the level of oxygen that we've measured on the summit of Mt. Everest. And it's amazing to me that patients could be sick for days, getting sicker, not realizing it.
Gayle King: So they had these very low oxygen levels, but they had no sensation of, "I can't breathe." Is that the point you're making?
Levitan: Yeah. Exactly.
King: You were surprised that some of them were still talking on cellphones. Why is that significant?
Levitan: You know, what is amazing to me with this disease is people's brains are working fine. … Their oxygen levels have gone down to scary low levels, but it has happened slow enough that their body has accommodated. So they are not like every other patient we see with serious lung disease … What I'm saying is this disease kills by silent hypoxia, and patients should understand that shortness of breath is a late sign.
King: Hypoxia is what, exactly?
Levitan: Low oxygen.
King: And the reason why it's so important to get this early warning is because it could avoid you being on a ventilator and having to be intubated, right?
Levitan: Absolutely. So, you know, we think this pneumonia basically has two phases. … This silent hypoxia period, where the oxygen's drifting down, but you feel okay. And then the second part of this disease, the part of this disease that kills, is when all of a sudden your lungs get stiff, carbon dioxide finally starts to build up, you begin to feel short of breath, and those patients are the patients who are presenting with COVID pneumonia.
King: By then, in some cases, it's too late. By the time you go to the hospital and you can't breathe, it's a very serious, often dire situation.
Levitan: Yeah, but let me just reassure people that what the lessons learned in New York are, are that we don't have to put in breathing tubes, even in most of the people who show up with advanced COVID pneumonia.
King: We don't?
Levitan: No. … They did a study of 50 patients, and what we learned is that even people who showed up with significant COVID pneumonia, we could keep off of ventilators three out of four of them. So 75% of patients didn't need ventilators. But they needed oxygen. They needed to do what we call positioning maneuvers. So we put them in different positions to help open up areas of their lungs.
King: How do you know, Dr. Levitan, when you should even check your oxygen levels?
Levitan: Let's talk about Germany. The Germans have the lowest death rates in Europe. What they do is every patient who has COVID, they visit every day and they check their oxygen and they check their vital signs. And so, what I'm saying to you is if you're having symptoms of viral illness, if you're known to have COVID, you should be checking your oxygen. … If you don't have an oximeter, increased breathing may be a sign of that, but also just feeling worse.
King: I think most people listening to you will now think, "I need to get an oximeter." Can you explain exactly what that is and how it works?
Levitan: Basically, you know, you just turn this little button on, and you put it on your finger, and within about 10 seconds or so, it displays your heart rate and your oxygen level. ... I think that oximeters in the midst of a respiratory pandemic, and for the next 12 to 24 months, that the public should think of an oximeter the way they do a thermometer. … It is a tool that they can have at their home that they can check, and that they can call up their doctor and say, "Hey, my pulse oximeter is reading consistently at this number. Is that something I need to be concerned about?"
King: I think every day we're learning something new about this COVID-19, and it seems to be such a moving target, always changing.
Levitan: What I'm telling you is actually hopeful. What we are learning about this disease is it attacks primarily through one pathway, and that's the lungs. We know when it is going to attack. It is going to attack between five to 10 days after infection. … And we know we have a way to detect it earlier, and that way is by close monitoring of pulse oximetry. … And what I'm saying to you is that as the public health messaging shifts, … we can move the treatment curve earlier and do much better for patients.
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Monday, 6 April 2020

April 06, 2020

Sorry Trump, there’s little evidence that hydroxychloroquine can treat Covid-19



Today President Trump again touted hydroxychloroquine as a potential treatment for Covid-19, despite a lack of good evidence that it is safe or effective against the coronavirus. Here’s what we do know about the drug Trump calls a ‘game changer’.

On Saturday the US Food and Drug Administration approved the use of two antimalarial drugs, hydroxychloroquine and a related medication, chloroquine, for emergency use to treat Covid-19. The drugs were touted by President Trump as a “game changer” for Covid-19.
However, a study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body. The study comes on the heels of two others – one in France and one in China – that reported some benefits in the combination of hydroxychloroquine and azithromycin for Covid-19 patients who didn’t have severe symptoms of the virus.
I am a medicinal chemist who has specialised in discovery and development of antiviral drugs for the past 30 years, and I have been actively working on coronaviruses for the past seven. I am among a number of researchers who are concerned that this drug has been given too much of a high priority before there is enough evidence to show it is indeed effective.
There are already other clinical studies that showed it is not effective against Covid-19 as well as several other viruses. And, more importantly, it can have dangerous side effects, as well as giving people false hope. The latter has led to widespread shortages of hydroxychloroquine for patients who need it to treat malaria, lupus and rheumatoid arthritis, the indications for which it was originally approved.
The idea that the combination of hydroxychloroquine with an antibiotic drug, azithromycin, was effective against Covid-19 gained more attention after a study published on March 17. This study described a trial of 80 patients carried out by Philippe Gautret in Marseille, France. Although some of their results appeared to be encouraging, it should also be noted that most of their patients only had mild symptoms. Furthermore, 85% of the patients didn’t even have a fever – one of the major telltale symptoms of the virus, thus suggesting that these patients likely would have naturally cleared the virus without any intervention.
In another study, posted on medRxiv, which has not yet been peer-reviewed, Chinese scientists from Renmin Hospital of Wuhan University, in Wuhan, China, gave hydroxychloroquine to patients with only mild infections who were free of medical issues, similar to the Gautret study. The results showed that the 31 patients who received the drug showed a lessening of their symptoms 24 hours earlier than patients in the control group. In addition, pneumonia symptoms improved in 25 of the 31 patients versus 17 of 31 in the control group. As noted in several of the comments associated with the manuscript, there are issues related to the translation of the paper, thus clouding interpretations of some of the results. The paper also appears to focus more on pneumonia than Covid-19. However, these issues may be cleared up or addressed once the paper finishes the peer-review process.
But two other studies have conflicting results.
A second French group, led by Jean-Michel Molina, has now tested the hydroxychloroquine-azithromycin combination treatment in 11 patients at the Hôpital Saint-Louis in Paris, France, and their results were strikingly different.
Like the Marseille study, the Molina trial was also a small pilot study. Molina and colleagues used the same dosing regimen as Gautret. In contrast, however, to the Gautret study, eight of the 11 patients had underlying health conditions, and 10 of 11 had fevers and were quite ill at the time the dosing began.
These Paris researchers found that after five to six days of treatment with hydroxychloroquine (600 mg per day for 10 days) and azithromycin (500 mg on day 1 and 250 mg on days 2 to 5), eight of the 10 patients still tested positive for Covid-19. Of these 10 patients, one patient died, two were transferred to the ICU and another had to be removed from the treatment due to serious complications.
April 06, 2020

BREAKING: Gov Makinde tests negative for coronavirus

The governor of Oyo State, Engr Seyi Makinde, has tested negative for coronavirus. This comes six days after he had earlier tested positive for the virus.
As contained in a tweet on Sunday night, on his handle, @seyimakinde, Makinde announced that he was resuming his duties as head of the Oyo COVID-19 task force on Monday.
“I am deeply moved by your prayers and support throughout this period. I am so thankful.
“This evening, I received my second negative test result for COVID-19. I especially thank Prof Temitope Alonge, who acted in my stead as Head of the Oyo State COVID-19 Task Force.
“I am also grateful to all members of the Task Force for their cooperation during this time.
“I will be resuming my responsibility as Head of the Task Force from tomorrow,” Makinde said.
JISTNET NEWS
 

Tuesday, 24 March 2020

March 24, 2020

Hantavirus: Man dies in China after testing positive to another virus


A man has died in Yunnan province of China after testing positive to Hantavirus. The man died while on his way back to Shandong Province for work on a chartered bus, China’s Global Times reports.
Humans who contract the hantavirus usually come into contact with rodents that carry the virus. “Rodent infestation in and around the home remains the primary risk for hantavirus exposure. Even healthy individuals are at risk for HPS infection if exposed to the virus,” Centre for Disease Control and Prevention said in its website.
Although HPS can’t be passed on from person to person, it can be contracted if someone touches their eyes, nose or mouth after touching rodent droppings, urine, or nesting materials, states Centers for Disease Control and Prevention fact sheet.

Sunday, 22 March 2020

March 22, 2020

Coronavirus: Don’t come to police stations, IG tells Nigerians

The Inspector-General of Police, Mohammed Adamu, has counselled Nigerians to avoid social visits to police stations and other police offices as confirmed cases of coronavirus rise to 30 in Nigeria.
He also urged the citizens to minimise official visits to police stations, except where absolutely necessary.
Adamu in a statement in Abuja on Sunday, by the force spokesman, DCP Frank Mba, also enjoined Nigerians to voluntarily adhere to directives guiding against the spread of coronavirus in the country.
The statement, with Ref No. CZ.5300/FPRD/FHQ/ABJ/VOL.2/, also quoted the IGP as warning against unnecessary arrests and detention of suspects, the jistnet report.
The statement read in part, “The IGP, while urging officers to observe personal safety measures, further directs the Zonal AIGs and Command CPs to ensure that cases of unnecessary arrests and detention of suspects are not condoned.

Wednesday, 11 March 2020

March 11, 2020

Nigeria to ban importation of hand sanitizers


Nigerian government on Wednesday said it is planning to ban the importations of hand sanitizers in order to bolster local production.
“I’m sure, as you all expect, that very soon, sanitizer will get into the list of items that are banned,” Central Bank governor Godwin Emefiele said in Abuja.
“It is naira that we will pay to buy sanitizers, rather than using dollars to import sanitizers from China,” he added.
Hand sanitizers have become coveted item since the confirmation of novel coronovirus in the country. Nigeria conformed the first case of coronavirus in February.
Although, Nigeria has only confirmed two people positive – a reality many scientists are curious about – the virus has infected more than 118,000 persons in 114 countries and led to, at least, 4,291 deaths.
There are now more than 100 cases recorded in 11 countries in Africa, according to the latest figures from the World Health Organization.
Egypt remains the nation with the most reported cases with 59, more than half of all confirmed cases on the continent.
The WHO has also declared the worldwide outbreak of the new coronavirus a pandemic.
“We have called every day for countries to take urgent and aggressive action. We have rung the alarm bell loud and clear,” WHO chief Tedros Adhanom Ghebreyesus said on Wednesday.

Monday, 2 March 2020

March 02, 2020

Why we invited Italian who brought coronavirus to Nigeria

The Industrial Director of Lafarge Plc, Mr Segun Soyoye, has said “the Italian who brought coronavirus to Nigeria came to inspect some installations of machines bought from a Swedish firm”.
He said this during an on-the-spot-assessment by Ogun State Government, Nigeria Centre for Disease Control, and World Health Organisation teams to Lafarge facility at Ewekoro on Saturday.
Soyoye added that the Italian didn’t go behind Lafarge the guest house at Ishofin Estate before he was evacuated, having developed abnormal temperatures that suggested he had been infected with Covid-19.
He added, “The Italian came for a business visit. He was in Lagos on Monday and slept at Airport Hotel, Ikeja. Our driver took him there.
“When we observed abrnomal temperatures and symptoms, we quickly instituted an Emergency Response Team which is led by the Company CEO. We have to find a way of analysing and identifying not only the Italian but also the other contacts.
“The contacts are now 39 and we have quarantined them, the house and clinic as well as the vehicles. We don’t take chances that is why they are put there.

5' 
CORONA

Why we invited Italian who brought coronavirus to Nigeria – Lafarge

The Industrial Director of Lafarge Plc, Mr Segun Soyoye, has said “the Italian who brought coronavirus to Nigeria came to inspect some installations of machines bought from a Swedish firm”.
He said this during an on-the-spot-assessment by Ogun State Government, Nigeria Centre for Disease Control, and World Health Organisation teams to Lafarge facility at Ewekoro on Saturday.
Soyoye added that the Italian didn’t go behind Lafarge the guest house at Ishofin Estate before he was evacuated, having developed abnormal temperatures that suggested he had been infected with Covid-19.
He added, “The Italian came for a business visit. He was in Lagos on Monday and slept at Airport Hotel, Ikeja. Our driver took him there.
“When we observed abrnomal temperatures and symptoms, we quickly instituted an Emergency Response Team which is led by the Company CEO. We have to find a way of analysing and identifying not only the Italian but also the other contacts.
“The contacts are now 39 and we have quarantined them, the house and clinic as well as the vehicles. We don’t take chances that is why they are put there.
All the guys on duty that day, they were also quarantined, so they will be there for 14 days as well.”
He also said its production lines were not shut as the guest house where the Italian was lodged is 5km to the manufacturing plants in Ewekoro.
The Team Leader of World Health Organisation in Nigeria, Mr Ibrahim Mamadu, commended the internal processes undertaken so far by Lafarge Africa to contain the deadly disease.
He however advised the company and others to acquire digital thermometers to check body temperatures instead of infrared thermometers for accurate body temperature readings.
“They will be there for 14 days. We will continue to observe them, we have their database, showing their biodata and other information.
“The doctor is here and what he is doing is to check them on a regular basis. So far, everybody is stable. They are not symptomatic, we are providing everything for them over there.
“The other thing that I have not said is that the clinic that was used for the infected person is closed, disinfected and we moved everybody out.

Wednesday, 26 February 2020

February 26, 2020

The coronavirus seems unstoppable. What should the world do now?

Residents of Casalpusterlengo, an Italian town under lockdown, line up to enter a supermarket.
 JISTNET IMAGES 


avoided using the word “pandemic” to describe the burgeoning crisis today, instead talking about “epidemics in different parts of the world.” But many scientists say that regardless of what it’s called, the window for containment is now almost certainly shut. “It looks to me like this virus really has escaped from China and is being transmitted quite widely,” says Christopher Dye, an epidemiologist at the University of Oxford. “I’m now feeling much more pessimistic that it can be controlled.” In the United States, “disruption to everyday life might be severe,” Nancy Messonnier, who leads the coronavirus response for the U.S. Centers for Disease Control and Prevention, warned on 25 February. “We are asking the American public to work with us to prepare for the expectation that this is going to be bad.”
capital firm. “The fight now is to mitigate, keep the health care system working, and don’t panic,” adds Alessandro Vespignani, an infectious disease modeler at Northeastern University. “This has a range of outcomes from the equivalent of a very bad flu season to something that is perhaps a little bit worse than that.”
Public health experts disagree, however, about how quickly the travel restrictions that have marked the first phase of the epidemic should be loosened. Early this week, the total number of cases stood at more than 80,000 with 2705 deaths—with 97% of the total still in China. Some countries have gone so far as to ban all flights to and from China; the United States quarantines anyone who has been in hard-hit Hubei province and refuses entry to foreign nationals if they have been anywhere in China during the past 2 weeks. Several countries have also added restrictions against South Korea and Iran.

Wednesday, 12 February 2020

February 12, 2020

Coronavirus: We’ve put measures in place to screen incoming passengers in airports ― Health Minister



The Minister of Health, Mr. Osagie Ehanire says the federal government have put measures in place at the airports to screen all passengers traveling into the country to ensure that the Coronavirus does not spread into the country.
Ehanire stated this on Tuesday while declaring open the Primary Healthcare summit organized by the Kano State government.
The Minister assured Nigerians that everything is done to prevent the spread of the virus into the country.
According to him, “Presently the challenges that we are all bracing up for which the Federal Government has been very anxious to see put in place to make sure that the Coronavirus circulating does not enter this country. We have set up response at the airports to reassure the public that everything is been done to screen all incoming passengers and have the readiness to be able to diagnose if it comes in.
“The two cases that came into Nigeria suspected to be coronavirus have been tested and turned out not be. We have three laboratories to test this virus.
“We are also working on emergency medical service and ambulance transport system for the whole country which will come up very soon in Abuja.
“This service will provide a linkage between the primary, secondary and tertiary healthcare. To create that network that is important in the service delivery,” the Minister stated.
He added that “we must commend the Governor for taking Kano state to be the lead performer in healthcare service delivery.
“Your excellency, your vision and mission are the same with that of President Muhammadu Buhari of improve quality health care delivery.
“Everything you do starts with foundation. Primary healthcare is the foundation of healthcare in anything you do.
“The primary healthcare sector will play a very large and important role in guaranteeing health care,” Ehanire said.
Earlier, Governor Abdullahi Umar Ganduje said the issue of enhancing primary health care in Kano state was his major cardinal thrust to make the primary health care formidable and robust adding that decisions had been taken to send a medical officer to all the 44 Local Government Areas in the State as a way of achieving 100% result of effective primary healthcare.

Monday, 10 February 2020

February 10, 2020

Kogi confirms nine cases of Lassa fever, four deaths


The Kogi State Ministry of Health has confirmed nine cases of Lassa fever with four deaths recorded since the outbreak of the deadly disease in the state about a month ago.
Dr Austin Ojotule, the State Epidemiologist, disclosed this in statement in Lokoja on Sunday.
According to Ojotule, the state’s statistics on Lassa fever outbreak update as at Feb. 8, 2020, has a total of 31 suspected cases.
He said out of the 31 suspected cases of Lassa fever, one was probable, 17 negative, nine confirmed, while five had pending laboratory results.
He said that four deaths had been recorded among the nine confirmed cases with Case Fatality Rate (CFR) of 44.4 per cent; the percentage of deaths from the confirmed cases.

Kogi confirms nine cases of Lassa fever, four deaths

The Kogi State Ministry of Health has confirmed nine cases of Lassa fever with four deaths recorded since the outbreak of the deadly disease in the state about a month ago.
Dr Austin Ojotule, the State Epidemiologist, disclosed this in statement in Lokoja on Sunday.
According to Ojotule, the state’s statistics on Lassa fever outbreak update as at Feb. 8, 2020, has a total of 31 suspected cases.
He said out of the 31 suspected cases of Lassa fever, one was probable, 17 negative, nine confirmed, while five had pending laboratory results.
He said that four deaths had been recorded among the nine confirmed cases with Case Fatality Rate (CFR) of 44.4 per cent; the percentage of deaths from the confirmed cases.
The official said that the nine confirmed cases were from five local government areas of Ibaji with two, Okene, two, Idah, three, Okehi, one, and Igalamela Local Government Area, one.
He, however, noted that contact tracing and follow-up were ongoing, adding that a total of 177 contacts had been line listed.
News Agency of Nigeria (NAN) reports that Lassa fever broke out in the state about a month ago.

Thursday, 30 January 2020

January 30, 2020

WHO declares coronavirus global health emergency Published 2 hours ago



World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus. Credit:
Fabrice Coffrini Getty Images
The World Health Organization on Thursday declared the outbreak of a novel coronavirus a global health emergency, an acknowledgement of the risk the virus poses to countries beyond its origin in China and of the need for a more coordinated international response to the outbreak.
WHO Director-General Tedros Adhanom Ghebreyesus made the announcement following a meeting of the WHO’s emergency committee. Last week, the committee had recommended that a public health emergency of international concern, or PHEIC, not be declared yet because of limited spread of the virus outside of China.
Tedros reconvened the committee this week because some other countries, including Japan, Germany, Vietnam, and, as of Thursday, the United States, had reported limited human-to-human transmission of the virus — a warning sign that the virus could start circulating more broadly outside China.
Members of the emergency committee had previously been divided over whether to recommend Tedros declare a PHEIC. Those opposed seemed to want to see if China’s efforts to control the outbreak could preclude broader worldwide transmission. Some 99% of the global cases have been in China, and the large majority of infections in other countries have been in people who picked up the virus while in China and then traveled to the other nations.
As of Thursday morning, there have been more than 7,800 confirmed coronavirus infections around the world, all but 82 of which were in China. There have been 170 deaths, all in China. Infections caused by the coronavirus, provisionally called 2019-nCoV , were first reported in December in the central Chinese city of Wuhan, though it’s possible the virus was spreading among people there before then.
The declaration comes as individual countries have started to close borders and restrict trade to China, and as airlines have halted some flights. Experts say such measures are not effective in stopping the spread of a virus and may discourage countries experiencing outbreaks from being forthright. The PHEIC gives Tedros certain additional authorities, including the ability to urge countries not to limit travel and trade, though the recommendations do not have to be followed.
Still, the PHEIC could rally some global coordination for a more unified response. Dr. Michael Ryan, the WHO’s emergency chief, told reporters Wednesday that 194 countries implementing unilateral trade and travel restrictions was an economic, political, and social “recipe for disaster.”
As they initially held off on calling a PHEIC, WHO officials stressed that they and national health officials around the world had still mounted a wide-reaching and aggressive response to the outbreak. At a press conference Wednesday, they seemed to lament that so much attention was paid to the binary of whether something was a PHEIC or not a PHEIC. Tedros said he wished it was more like a stop light, with yellow serving as a warning.
It’s seen as “PHEIC, no PHEIC, either green or red,” Tedros said. “I think we have to revise that. It would be good to have the green, the yellow, and then the red, something in between. … There could be some intermediate situation.”
Also Thursday, the WHO said it plans on provisionally calling the disease caused by the virus “2019-nCoV acute respiratory disease” until officials settle on a name.
China has taken unprecedented steps to try to contain the outbreak, quarantining tens of millions of people in Wuhan and other cities by shutting down travel within, to, and from the areas. Experts, however, say, it’s not clear such massive efforts are likely to prove effective, given that the virus seems to be spreading in many locations in China and that the lockdowns could keep or drive people away from seeking care if they are sick.
In the United States, officials have been screening passengers arriving from Wuhan for signs of illness and informing them to call a health care provider if they start to get sick. (Officials from the Centers for Disease Control and Prevention have said the number of people arriving from Wuhan has dropped since China imposed the travel ban from there, but that they were continuing with their screening policies.) The CDC has also boosted surveillance at 20 entry points where officials are normally based in case an arriving traveler shows signs of a disease.
There had been five confirmed cases of the coronavirus in the United States, all related to travel to China. But just hours before the WHO declared the PHEIC, the CDC announced that one of those people — a woman in Illinois — had passed the virus on to her husband . U.S. officials had anticipated an incidence of such limited transmission and are working to prevent any broader spread of the virus.
WHO officials have said if sustained transmission of the virus occurs outside China, it becomes much harder to stop overall.
The virus can cause severe cases of pneumonia and milder cases of cough and fever, according to studies of early infections in Wuhan. It’s likely that authorities have not been able to keep track of many mild cases, including people who were not sick enough to seek care, and researchers have documented cases of the virus in people showing no symptoms.
It’s not clear if people need to be showing symptoms to pass the virus on, though even if asymptomatic people can spread the virus, they may be less likely to than people who are sneezing and coughing — routes for the virus to jump from one person to another.
Coronaviruses, a family that includes SARS and MERS, are thought to originate in bats and can jump from there or another animal to humans. Many of the early cases in Wuhan — though not all — were tied to a seafood market that also sold live animals for meat.
The emergence of a global coronavirus outbreak from China is reminiscent of the SARS outbreak of 2002 to 2003, which went on to kill nearly 800 people. The PHEIC designation was created following an update to the International Health Regulations after that outbreak.
The first PHEIC was declared for the 2009 H1N1 flu pandemic, and others have included the 2014-2016 West African Ebola outbreak and the Zika outbreak in 2016. The WHO set up an emergency committee to assess whether MERS should be declared a PHEIC, but it concluded after meeting several times that the disease did not constitute a global health emergency.
Ahead of WHO’s decision Thursday, there were two active PHEICs: the ongoing Ebola outbreak in the Democratic Republic of the Congo and the continued transmission of polio.

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